Companion Animal Vaccines | Esco VacciXcell

Companion Animal Vaccines

As with human diseases, it is also better to prevent our pets to catch diseases than to spend more on treatment. The American Animal Hospital Association (AAHA) groups companion animal vaccines into two categories: core and non-core vaccines. Core vaccines are recommended for all cats or dogs while non-core vaccines are administered based on risk factors (geographical area and pet’s lifestyle). The initial immunity provided by the mother’s milk only lasts for a few weeks thus, at 6 to 8 weeks of age, the pets should receive first rounds of vaccination.

Feline vaccines
Naïve kitten/Animals that have never been vaccinated
Core Combination: Panleukopenia virus (FPV), Feline Herpesvirus-1, Feline Calicivirus (FHV-1/FCV) 6 weeks
Core Rabies 8-12 weeks
Non-core Feline Immunodeficiency Virus 8 weeks
Non-core Bordetella bronchiseptica 8 weeks
Non-core Feline Leukemia Virus 8-12 weeks
Non-core Chlamydophila felis 9 weeks
Core Combination: Panleukopenia virus (FPV), Feline Herpesvirus-1, Feline Calicivirus (FHV-1/FCV) – 2nd injection 10 weeks
Non-core Feline Immunodeficiency Virus (2nd injection) 10 weeks
Non-core Feline Immunodeficiency Virus (3rd injection) 12 weeks
Non-core Chlamydophila felis (2nd injection) 13 weeks
Non-core Feline Leukemia Virus (2nd injection) 12-16 weeks
Core Combination: Panleukopenia virus (FPV), Feline Herpesvirus-1, Feline Calicivirus (FHV-1/FCV) – 3rd injection 14 weeks
Continued immunization for adult cat
Core Combination: Panleukopenia virus (FPV), Feline Herpesvirus-1, Feline Calicivirus (FHV-1/FCV) Every 3 years
Core Rabies Annual (or as required by regulations)
Non-core Feline Leukemia Virus Annual
Non-core Feline Immunodeficiency Virus Annual
Non-core Chlamydophila felis Annual
Non-core Bordetella bronchiseptica Annual
Canine vaccines
Naïve pup/Animals that have never been vaccinated
Core Combination: Distemper virus, Parvovirus, Adenovirus-2, Parainfluenza virus 6 weeks
Non-core Combination: Bordetella, parainfluenza virus 8 weeks
Non-core Leptospira 8-9 weeks
Non-core Canine Lyme disease 8-9 weeks
Core Combination: Distemper virus, Parvovirus, Adenovirus-2, Parainfluenza virus (2nd injection) 10 weeks
Non-core Leptospira (2nd injection) 10-11 weeks
Non-core Canine Lyme disease (2nd injection) 10-11 weeks
Core Rabies 12 weeks
Core Combination: Distemper virus, Parvovirus, Adenovirus-2, Parainfluenza virus (3rd injection) 14 weeks
Continued immunization for adult dog
Core Combination: Distemper virus, Parvovirus, Adenovirus-2, Parainfluenza virus (2nd injection) Every 3 years
Core Rabies Annual or every three years (depending on product label)
Non-core Combination: Bordetella, parainfluenza virus Annual
Non-core Leptospira Annual
Non-core Canine Lyme Disease Annual
Rabbit vaccines
Naive bunny/Animals that have never been vaccinated
Myxomatosis 5 weeks
Rabbit Haemorrhagic Disease Virus (RHD1) 6-12 weeks
Rabbit Haemorrhagic Disease 2 (RHD2) 6-12 weeks
RHD1 – 2nd injection 10-16 weeks
Continued immunization for adult rabbit
Myxomatosis Annual
RHD1 Annual
RHD2 Annual (2 weeks from Myxomatosis and Rabbit Haemorrhagic Disease Virus vaccination)
Pet bird vaccines
Naive / Animals that have never been vaccinated
Polyomavirus 3 weeks
Polyomavirus – 2nd injection 6-12 weeks
Continued immunization for adult rabbit
Polyomavirus Annual
Cancer vaccines

A new neoantigen source has been recently discovered arising from RNA transcription and splicing errors. These frameshift neoantigens were demonstrated by Stephen Johnston and his team to offer partial protection in mouse models for melanoma and breast cancer. With these findings, a large canine cancer vaccine trial was initiated to test for broadly protective prophylactic cancer vaccine utilizing pooled frameshift neoantigens.

References:
  1. American Animal Hospital Association (2018). Canine Vaccination Guidelines. Last accessed 31 July 2019 from http://www.mybhph.com/wordpress/wp-content/uploads/2018/02/canine_vacc_guidelines.pdf
  2. American Association of Feline Practitioners (2006). Feline Vaccination Guidelines. Last accessed 31 July 2019 from https://catvets.com/public/PDFs/PracticeGuidelines/VaccinationGLS-summary.pdf
  3. Australian Veterinary Association (2011). Vaccination of Rabbits and Ferrets. Last accessed 19 August 2019 from https://www.ava.com.au/policy-advocacy/policies/unusual-pets-and-avian/vaccination-of-rabbits-and-ferrets/
  4. Shen, L., Zhang, J., Lee, H. et al. RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for Vaccines. Sci Rep 9, 14184 (2019) doi:10.1038/s41598-019-50738-4