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mAbs for diagnostics | Esco VacciXcell

mAbs for diagnostics

Biological assays such as Enzyme-linked immunosorbent assay (ELISA) and Fluorescence in situ hybridization (FISH) utilize the high specificity of monoclonal antibodies towards specific antigen.

mAbs can be produced for any antigen; production can be achieved thru in vivo production (harvesting from mouse ascites), hyrbidoma cell line, or recombinant production.

Molecular diagnostics can be categorized into three types: in vivo, in vitro and disease diagnostics.

In vitro Diagnostics (IVD)

IVDs are a collection of tests that are used to detect infections, diseases, allergies and other medical conditions. Most IVD tests are performed in the laboratory or professional healthcare clinics. The applications of IVD in medical diagnosis are vast and includes disease detection, regenerative medicine monitoring and tests of blood for transfusion. One technique widely used in IVD is the Sandwich ELISA, a type of ELISA that uses two layers of monoclonal antibodies to quantify antigens. In this type of system, the mAb act as either the capture or detection antibody.